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Chloride is often measured along with other electrolytes to diagnose or monitor conditions such as kidney disease, heart failure, liver disease, and high blood pressure. Reviewed December 2, 2015. Rare side effects include: Infections rarely occur if the person performing the blood draw follows proper procedure. It’s usually ordered with other blood tests when you are having your cholesterol, blood sugar, and other electrolytes such as sodium and potassium checked. The sample is promptly sent to a medical laboratory for analysis. Our website services, content, and products are for informational purposes only. Our science team must pass long technical science tests, difficult logical reasoning and reading comprehension tests. We do not aim to diagnose, treat, cure or prevent any illness or disease. As a result, they reduce the reabsorption of sodium, potassium, and chloride in the kidneys. The normal range for blood chloride is between 96 and 106 milliequivalents of chloride per liter of blood (mEq/L). These conditions include alkalosis, which happens when your blood is either too alkaline or basic, and acidosis, which happens when your blood is too acidic. For instance, a loss of fluid due to vomiting or diarrhea may lower your chloride levels. You might have some slight pain or bleeding at the blood draw site. What Is Red Cell Distribution Width on a Complete Blood Count? Alkalosis, a condition in which you have too much base in your blood. Your health care provider may recommend a urine chloride test in addition to the blood test to get more information about your chloride levels. Brigham and Women’s Hospital: “Serum Electrolytes.”, University of Rochester Medical Center: “Chloride.”, University of Maryland Medical Center: “Distal renal tubular acidosis.”, UCSF Medical Center: “Serum Chloride.”, American Heart Association: “What is Heart Failure?”, Merck Manual: “Metabolic Acidisis,” “Hyperaldosteronism.”. Hyperchloremia is an electrolyte disturbance in which there is an elevated level of the chloride ions in the blood. The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. Speak with your doctor to determine if your test results indicate an issue. High chloride levels may be an indication of hyperchloremia. We believe that the most accurate information is found directly in the scientific source. It can be measured with a blood test, typically as part of an electrolyte or metabolic panel. Bethesda (MD): U.S. Department of Health and Human Services; What Are the Risks of Blood Tests? Chloride is an essential electrolyte (a mineral that conducts electricity when in water). Our goal is to not have a single piece of inaccurate information on this website. This will help your doctor figure out where to look for the condition or medication that might be causing your imbalance. The chloride blood test, or serum chloride level, is often a part of a comprehensive metabolic panel or a basic metabolic panel. It can also be measured via sweat, serum, urine, and feces, in certain circumstances. Your doctor will call you with the results. This test is performed via a simple blood draw, and there are no major risks involved. Abnormal chloride levels do not necessarily mean that you are suffering from a certain condition. Kenilworth (NJ): Merck & Co Inc.; c2017. Different things can cause chloride levels to elevate, so if you have symptoms that signal hyperchloremia, you may want to confirm that through a chloride test. Hypochloremia occurs when your chloride level is low. Low chloride levels may mean that you are suffering from a condition called hypoglycemia. Though these fluids are often life-saving, it is not uncommon for the concentration of chloride to become abnormal.. For instance, if the blood contains excess solid material (excess triglycerides or plasma cell cancer), it can interfere with the electrode, incorrectly registering as lower chloride levels [6, 7]. nonsteroidal anti-inflammatory drugs (NSAIDs). Please contact your health care provider with questions you may have regarding medical conditions or the interpretation of test results. One of the best ways to manage hyperchloremia or high chloride in blood is by making lifestyle changes. If you’re having symptoms such as weakness, constant tiredness, or dehydration, your doctor may order a chloride test. Normal chloride levels in children and adults are 95-105 mEq. Carlos is passionate about learning the mechanisms behind biological processes and communicating science to both academic and non-academic audiences. They’ll draw a blood sample using a small needle and then cover the puncture site with gauze or a bandage. Someone will clean the area. In addition to the above, it also includes glucose, calcium, and tests of kidney function. It may also be included as part of a comprehensive metabolic panel (CMP), which includes additional tests. Available from: University of Rochester Medical Center [Internet]. Chloride, Serum; p. 153–4. Your serum chloride levels are affected by various factors, and other labs may be using a different method that could impact your result. The symptoms that may indicate a chloride imbalance include: For accurate results, you shouldn’t drink or eat anything during the eight hours leading up to the test. To learn what your results mean, talk to your health care provider. It helps keep the amount of fluid inside and outside of your cells in balance. Corticosteroid drugs such as cortisone and hydrocortisone bind to the aldosterone receptor and also activate the absorption of these electrolytes [25, 2]. More serious health conditions, such as heart, kidney, or liver disease, can be related to abnormal blood chloride levels. It can be measured with a blood test, typically as part of an electrolyte or metabolic panel. Required fields are marked *. Read our, Medically reviewed by Kashif J. Piracha, MD, Medically reviewed by Douglas A. Nelson, MD, Medically reviewed by Elizabeth Molina Ortiz, MD, MPH. Carbonic anhydrase II transforms carbon dioxide into bicarbonate. But, used in combination with your medical history, exam, and other tests, it can help play a role in diagnosis. It is best to talk with your doctor to know if your result is a sign of a health problem. The main ones are [19]: Thiazides and thiazide-like diuretics increase water elimination by blocking the Na+/Cl- cotransporter, which prevents the absorption of sodium and chloride in the kidneys. Chloride ion has a negative charge, and it is notated as CL-. The anion gap is usually used to estimate the blood levels of other electrolytes and diagnose acid-base disorders. We are dedicated to providing the most scientifically valid, unbiased, and comprehensive information on any given topic. Tell your doctor about any medications you take and whether they’re over-the-counter (OTC) or prescription drugs. Chloride: The Test; [updated 2016 Jan 26; cited 2017 Mar 12]; [about 3 screens]. There is very little risk to having a blood test. Some other key electrolytes are: These electrolytes work together synergistically, in that the concentration of one sometimes affects the concentration of another. Depending on the context, results might be available within a couple of hours or in a day or two. These are substances of very small size, called ions, that carry either a positive or a negative kind of charge. Philadelphia: Wolters Kluwer Health, Lippincott Williams & Wilkins; c2014. Talk with your doctor about your test results, especially if you’re outside the healthy range. Save my name, email, and website in this browser for the next time I comment. Conversely, electrolytes like iodide and bromide or drugs like salicylate can be incorrectly picked up by the electrode and register as higher chloride levels (such as in case of poisoning) [8, 9, 10]. Joe Cohen won the genetic lottery of bad genes. In most cases, you’ll get your blood chloride checked along with other basic laboratory tests. To use the sharing features on this page, please enable JavaScript. Hinkle J, Cheever K. Brunner & Suddarth's Handbook of Laboratory and Diagnostic Tests. Hyperchloraemia also occurs when too much alkaline fluid is lost from the body (producing metabolic acidosis ), or when a person hyperventilates (causing respiratory alkalosis ). However, the long-term use of corticosteroid drugs causes a condition called Cushing’s syndrome in which the glands above the kidneys are damaged and the production of aldosterone and other corticosteroid hormones stops. Though it’s normal for electrolyte levels to…. Our science team is put through the strictest vetting process in the health industry and we often reject applicants who have written articles for many of the largest health websites that are deemed trustworthy. The person performing the blood draw will clean the area with antiseptic to help prevent infection.

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